Resistance to antibiotic and also the side effects of drug consumption are the main problem in antibiotic treatment. Therefore, after doing researches on the plants properties, humankind has attempted to use them in different industries. In this investigation the anti-microbial effects of ethanolic extracts of four medicinal plants from Ardebil province include Nepeta nuda, Salvia verticilata, Nepeta crassifolia and Teocrium chamaedry subsp. syspirense