In this review which was carried out on 20 patients suffering from typhoid fever the following results were observed:
90% of the patients were under 30 year of age and 75'X, were female. They were hospitalized an average of J 1.75 days after onset of the disease.
The most common symptoms were fever and headache at the onset of the disease and during hospitalization. The most important clinical signs and sympthoms of disease was apathy. rose spots, and hepatosplenomegaly.
The blood cultures were positive in 50% of the cases, an important point is to preserve the blood culture for at least one week, since in 70% of the cases the blood cultures were positive one week later.
The stool cultures were positive in only 3 pa
tients. only in 14 cases widal test was performed
showing a titre of 1-10 or more. Anemia with a Hb < IOgo/,, was found in 20'}{, of the cases. The leukocytes were normal in 70','{,, and leukopenia was found only in 25"{,.
One of the interesting lab-test results was an increase of L D H, for more than 500 units in 95% of the cases and more than 1000 units in 55'Y., which was reduced after treatment. We hope to be able to distinguish and determine the saurce of the increase of L D H in typhoid fever in our future studies of concerning !so-enzymes.
There was no relapse of the disease and readmission to the hospital.
Only in one patient intestinal perforation was encountered which on whom a surgical operation was performed.
In order to assess the effectiveness of different medication on typhoid fever 17 additional patients were studied, effectiveness of the following antibiotics with regard to the remission of the fever were as follow: Ampicillin, chloromphenicol, cotrimoxasol and amoxicillin.
We found two cases of relapse in patients whom treated with chloramphenicol, and two cases of treatment failure one with amoxicillin and other with cotrimoxasol.