Abstract: Background: H.pylori infection has been found to be associated with different diseases such as gastritis, peptic ulcer and malignancy. The present study was conducted to compare helicobacter pylori antibody in rural and urban children in Qazvin. Materials and methods: During this case-control study, 150 children aged 2-month to 12-year (75 urban and 75 rural children) who had been referred to Ghazvin Ghods Children hospital affiliated to Ghazvin University of Medical Sciences were included. Two groups of urban and rural children were matched according to age and sex. Serum IgG and IgA antibodies titer of H.pylori were determined by ELISA method. Results: Of 150 children, 23(12.3%) had positive antibodies titer against H.pylori., of whom 9 (12%) were urban and 14(18%) were rural children (NS). Conclusion: There was no statistically significant difference between rural and urban children, however, rural children were more commonly infected. KEYWORDS: Helicobacter pylori, Serum IgA, Serum IgG, Children

Keywords: Helicobacter pylori, Serum IgA, Serum IgG, Children

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