Volume 46, Issue 3 (9-2022)
Research in Medicine 2022, 46(3): 136-144 |
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Ethics code: IR.SBMU.MSP.REC.1399.24
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tavakolian S, Goudarzi H, Faghihloo E. Prevalence of Herpes Virus Type1 in Cancerous and Healthy Breast Tissue Samples in Iran. Research in Medicine 2022; 46 (3) :136-144
URL: http://pejouhesh.sbmu.ac.ir/article-1-3145-en.html
URL: http://pejouhesh.sbmu.ac.ir/article-1-3145-en.html
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract: (616 Views)
Background and Aim: Statistics have shown that breast cancer is the second common cancer in most countries of the world. Many factors can have detrimental effects on this disease and herpes simplex virus type 1 is likely to be one of the items related to breast cancer due to the oncogenic proteins of this virus and its ability to stimulate the immune system. In the present article, we evaluated the prevalence of this virus in breast samples of patients in Tehran.
Methods: In the current case-control study, 40 breast cancer tissues and 50 healthy adjacent ones were collected from Taleghani and Imam Hossein Hospitals in Tehran, between 2017 and 2021. After DNA extraction, the prevalence of herpes simplex virus type 1 in breast samples was investigated.
Results: Our results showed that more than 50% of the cancer samples were in phase III-IV and one of the healthy tissues showed the herpes simplex virus type 1 infections.
Conclusion: It seems that herpes simplex virus type1 prevalence in breast cancerous tissues is likely to be lower in comparison with healthy ones; however, this conclusion requires further research, due to the small number of samples in our study.
Methods: In the current case-control study, 40 breast cancer tissues and 50 healthy adjacent ones were collected from Taleghani and Imam Hossein Hospitals in Tehran, between 2017 and 2021. After DNA extraction, the prevalence of herpes simplex virus type 1 in breast samples was investigated.
Results: Our results showed that more than 50% of the cancer samples were in phase III-IV and one of the healthy tissues showed the herpes simplex virus type 1 infections.
Conclusion: It seems that herpes simplex virus type1 prevalence in breast cancerous tissues is likely to be lower in comparison with healthy ones; however, this conclusion requires further research, due to the small number of samples in our study.
Type of Study: Original |
Subject:
Virology
Received: 2022/01/16 | Accepted: 2022/06/1 | Published: 2023/01/2
Received: 2022/01/16 | Accepted: 2022/06/1 | Published: 2023/01/2
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