Volume 44, Issue 4 (6-2020)                   Research in Medicine 2020, 44(4): 587-593 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mohammadi Dahj M, Amiri F, Deyhim M R, nikoogftar zarif M. The evaluation of oxidative stress in platelet during storage of platelet concentrate. Research in Medicine. 2020; 44 (4) :587-593
URL: http://pejouhesh.sbmu.ac.ir/article-1-2089-en.html
Blood Transfusion Research Center,High Institute for Research and Education for Transfusion Medicine , mrdeyhim@yahoo.com
Abstract:   (1546 Views)
Background and aim
During platelet storage, is
Materials and Methods
In this experimental study, 10 bags of platelet concentrate prepared by PRP (Plasma –rich platelet) method were evaluated. Research variable included mitochondrial  
According to the results, ROS (37±16.22), MDA (22.2±11.6) concentration and LDH enzyme activity (3680±310) increased significantly (P<0.001) while PLT count was significantly decreased (P<0.001). The concentration of all the days of platelet.
According to the results of this study, it was observed that oxidative damage occurred in platelet with increasing radical oxygen species and lipid peroxidation which can reduce platelet count and platelet viability during platelet storage. Using anti-oxidant as an additive in platelet concentrate may decrease oxidative damage and increase platelet viability and quality during storage.
Full-Text [PDF 658 kb]   (242 Downloads)    
Type of Study: Original | Subject: Hematology
Received: 2019/08/27 | Accepted: 2020/01/8 | Published: 2020/06/27

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Creative Commons License
This Journal is licensed under a Creative Commons Attribution 4.0 International License  | Research in Medicine

Designed & Developed by : Yektaweb