Research in Medicine

Mendeley  

Zotero  

Balouch F, Mohammadi M, Asad Afrooz G. Effect of sesame peel extract lozenge on gag reflex. Research in Medicine 2021; 45 (3) :1-5
URL: http://pejouhesh.sbmu.ac.ir/article-1-2143-en.html

Background and Aims: Gag is a common complication during dental surgeries that can make the treatment problematic or even impossible. Previous studies have suggested various non-medicated interventions, such as distracting the patient, behavior therapy, hypnosis, acupuncture, and some  medications such as application of sedatives like Nitrox ide 30%, Midazolam, and oral Metobenzamid as well as herbal substances, such as date extract  and ginger. Using elaeagnus angustifolia extract for removing Gag reflex is another method which has received very little attention in literature. Thus, we made an attempt to examine the effect of elaeagnus angustifolia extract suck pills on gag reflex in the Dentistry Faculty in 2015.
Materials and Methods: A clinical trial was performed on 45 patients. Case group (Experimental 2) sucked the elaeagnus angustifolia extract tablet and control group received no intervention and placebo group (Experiment 1) was given a simulated non-extractable drink tablet similar in color and size to those of the original sample. The main condition for inclusion in the study was reflex of nausea and their consent to participate in the study. The tablet was manufactured ex vivo and then examined for nausea in random patients with mild stimulation of the palate with patients showing the appropriate level of feeling on a Glascow scale ruler. The patients with level 10 of nausea sucked the pill for 4 minutes and then we immediately stimulated them using abselang to measure the nausea on the patient's ruler.
Results: The pre-intervention and mild subtype of nausea reflex were 10.6 in the control group, 10.8 in the placebo group, and 10.8 in the case group and 15.2, 14.8, and 15.4 in the mean group, respectively. Finally, in the severe subgroup, the values obtained were 17.6, 18, and 17.4, respectively, with insignificant differences (P <0.09).
Conclusion: It seems that elaeagnus angustifolia extract can reduce Gag reflex. However, we suggest that more extensive studies be carried out in this area.