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Background and Aim: Reducing of any mobility and activity cause many diseases as cardiovascular diseases.  Therefore, the aim of this study is an investigation on The effect of a combined training period (aerobic and High Intensity Interval Training) and high intensity interval training on Homocysteine and ESR in cardiovascular patients.
Materials and Methods: In this experimental study, 32 cardiovascular patients were selected voluntarily and randomly divided into 3 groups: combined training group (n = 10), HIIT training group (n=11) and control group (n = 11). Inclusion criteria included injection fraction greater than 30, lack of tachycardia and bradycardia, and lack of functional capacity less than 5 met. Exclusion criteria also included unwillingness to continue the activity and diagnosis by a physician. The protocol of the combined training group consisted of performing 2-3 times a week of CAET training without performing HIIT exercises during the first 4 weeks, then performing 2 times a week of CAET training and performing once a week of HIIT training during the second 4 weeks. The protocol of the HIIT training group included performing 2-3 times a week of HIIT training during the first 4 weeks and performing 3 times a week of HIIT training during the second 4 weeks. Blood samples were taken 24 hours before the first training session and 48 hours after the last training session (under the same conditions for all three groups). Data analysis was performed using paired sample t-test , ANOVA and post hoc at a significance level of P˂0.05.
Results: The Performing combined exercises and HIIT has a significant effect on reducing serum homocysteine levels(Combined exercise (baseline values of 19.7± 1.3, after intervention 13.8 ± 2.3,P˂0/00), HIIT exercise (baseline values of 20.0± 1.3, after intervention of 16.3± 1.5, P˂0/001)) and ESR levels(Combined exercise (baseline values 27.7 ± 2.1, after intervention 22.13 ± 1.27, P˂0/005), HIIT exercise (baseline values 26.2 ± 2.8, after intervention 22.9 ±2.0, P˂0/004)) compared to the control group(Homocysteine P˂0/619, ESR P˂0/306 of cardiovascular patients.
 Conclusion: combined and HIIT training seem to be effective in reducing homocysteine and ESR in cardiovascular patients, while the effect of combined exercise is greater than HIIT.

Type of Study: Applicable | Subject: Physical Education and Sports Science ( Sport physiology- Sport biomecanic
Received: 2020/08/18 | Accepted: 2021/01/25

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