Showing 8 results for Nemati
Ebrahim Nemati Pour, Vahab Fatoorechi,
Volume 7, Issue 1 (Spring 1981)
Abstract
One of the most important advances in imsulin therapy has been the commercial production of highly purified single peak and single component insulin. The routine use of these pre9ara -tions have reduced insulin allergy and abolished insulin lipoatrophy.
The subject of low dose insulin infusion in diabetic keto - acidosis in still controversial,but is based on sound theoreti - cal and experimental basis and offers advantages over the ciassic method. We believe that its routine use should be allowed only under expert supervision. Artificial pancreas is on its way for routine application in treatment of acute conditions in hospitalized patients and in diabetic coma. Chronic use of artificial pancreas for management of diabetic patients has to wait for further technical advances.
, , , Ehsani Ardakani Mj, Mohaghegh Shalmani H, Nemati E, Zali Mr ,
Volume 30, Issue 2 (6-2006)
Abstract
Frequency of helicobacter pylori among patients with diabetes mellitus
: Research Center for Gastroenterology and Liver Disease, Shaheed Beheshti University of Medical Sciences
Abstract:
Background: It is believed that diabetes mellitus (DM) increase the susceptibility to Helicobacter Pylori (HP) infection, but there is little information about the role of DM in being infected patients with HP. We studied the frequency of HP in diabetic patients referred to Taleghani hospital during 2003-2004.
Materials and methods: In this case–control study, frequency of HP in diabetic patients referred to Taleghani hospital were studied. Case group consisted of 84 patients with documented diabetes mellitus and control group included dyspeptic patients without DM who were been matched to the case group. Both case and control groups underwent endoscopy. Patients who had history of using antibiotics during the previous month or proton pump inhibitors during the past week were excluded. Urease test was performed in all patients. In negative unease test, biopsy was taken to evaluate histologic study of HP.
Results: Mean age of case and control groups were 47.5±10.2 and 47.6±10 years, respectively. In both groups, male to female ratio was 46 to 36. Nineteen patients (22.6%) have diabetes type1 and others (77.4%) have diabetes type 2. Frequency of HP in case and control groups were 47 (51.1%) and 45 (48.9%), respectively and there was no significant differences between two groups. Odds ratio for being infected with HP in diabetic patients was 0.95 (95% CI: 0.7 – 1.3).
Conclusion: This study didn’t demonstrate any relation between DM and HP in adult patients. So, high frequency of dyspepsia in diabetic patients can be attributed to other factors such as autonomal disorders.
KEYWORDS: .
Md Arash Mohammadi Tofigh, Md Gholamhossein Hayatollah, Md Khosro Ayazi, Md Mohammad Ali Hosseinian, Md Behzad Nemati Honar, Msc Farshad Safdari,
Volume 38, Issue 3 (11-2014)
Abstract
Abstract Background: In recent years, many authors considered the effects of honey in treatment of different types of wounds. Pressure ulcers are one of the most important health problems with a challenging treatment. In current study, we evaluated the effects of an ointment containing honey, sesame and camphor in treating pressure ulcers in diabetic patients. Materials and methods: In current randomized clinical trial, 60 patients assigned to two groups randomly. Daily irrigation using normal saline and dressing with sterile gauze was performed. In control group, placebo and in case group, the ointment containing honey, sesame and camphor (Kimia ointment) was used twice a day for 8 weeks locally. Before and after the treatment, PUSH tool 3.0 was completed. Also, the rate of infection requiring surgical debridement was compared between groups. Mann-Withney U, Wilcoxon and chi-square tests were used. Results: Two groups were the same in terms of sex and age. There were one and 5 patients required surgical debridement in case and control groups, respectively (p=0.195). The PUSH score decreased significantly in two groups after the treatment (p<0.001). Before the treatment, the PUSH scores were the same. At the last visit, the PUSH score in ointment and placebo group was 4.9±1 and 6.8±1.2, respectively (p<0.001). Conclusion: Treating pressure ulcers in diabetic patients applying ointment-containing honey, sesame and camphor can be helpful in accelerating the healing process. However, more extensive studies are needed.
Mojgan Mokhtari, Mitra Nemati, Minoo Yaghmaei, Leila Nazari,
Volume 44, Issue 3 (9-2020)
Abstract
Background: The pain after the surgery is an important clinical problem. Until now a lot of methods for reducing pain after surgery have been evaluated. Because of the high prevalence of cesarean section and this point that pain after cesarean section can influence the healthy state of mothers and infants, this study with purpose of comparing of outcome of incisional infiltration with Lidocaine and Epinephrine versus Lidocaine in the end of cesarean section has been planned.
Materials and Methods: This study has been performed on 100 pregnant women with term pregnancy that were candidate for elective cesarean with spinal anesthesia. Patients were randomly divided to two groups including, group of 20 ml 2% Lidocaine or 20 ml solution of 1/4 of 1 mg/ml Epinephrine in 50cc of 2% Lidocaine (1/200000 dilution) that has been infiltrated in the subcutaneous after cesarean and before closing the skin. The measure of pain and narcotic use after surgery, the time of first lactating, to get out of bed , and discharge time of patients from hospital were compared between two groups with statistical tests, independent t, fisher exact test , and chi-square .
Findings: The results of this study showed that patients who have received Lidocaine and Epinephrine in the incisional site after cesarean versus patients who have received Lidocaine alone meaningfully started lactating sooner (P=0.018) and discharged sooner from hospital (P=0.010). Also, these individuals experienced less pain intensity from the 4 hours postoperatively until the end of the first day after the operation, compared to the lidocaine group (P<0.001), and the use of pethidine on the first day was less than that of the opposite group (P<0.001).
Conclusion: It seems adding Epinephrine to the local anesthetics like Lidocaine can prolong the effect of anesthetics and can reduce the doses of narcotic use after surgery and also can reduce the time of first lactating and discharge from hospital.
Esmat Barouti, Sara Nemati,
Volume 44, Issue 4 (12-2020)
Abstract
Background: Gestational Diabetes Mellitus (GDM) is one of the common metabolic diseases among pregnant women that needs delicate monitoring and control to improve the metabolic condition and to reduce pregnancy complications. Despite scarce data on the effect of probiotic supplementation on glycemic control and serum lipids concentrations in women with GDM, probiotic supplements and their effects on pregnancy outcome have become the center of focus in research. In the present study, we aimed to determine the impact of probiotic supplementation on glycemic control, lipid profiles, pregnancy, and infancy outcomes in GDM patients.
Methods: In the current clinical trial, 120 GDM patients underwent a specific diet. Patients were divided into two separate groups to receive either probiotic supplements (N=60) or a matching placebo (n=60). The study groups received nutrition counseling and the patients received treatment for six weeks. Demographic characteristics (participants’ age, gestational age, gravidity, and BMI) were evaluated and serum levels of Fasting Blood Sugar (FBS), Triglyceride, Total cholesterol, LDL cholesterol, and HDL cholesterol were examined before and after the intervention, respectively. Besides, weight of the newborn infants, Apgar scores, the requirement of using insulin among pregnant mothers, and pregnancy outcomes were examined carefully.For statistical analysis, SPSS, version 20, was used running Student›s t and Mann-Whitney U tests
Results: There were no significant differences in demographic characteristics between the two groups. All the participants were in the early second trimester period. After six weeks of intervention, probiotic supplementation resulted in a significant decrease in FBS (p=0.01) and the requirement for insulin administration was significantly lower in comparison with the control group (P=0.026). In addition, we observed elevated lipid profiles in both groups. A significant rise in serum HDL (P=0.01) was also observed following supplementation with the probiotics and a significant elevated serum level of LDL in the control group (P=0.01). In the group with the probiotic supplementation diet, the weight of newborn infants (P=0.001) and pregnancy complications (P=0.028) were also significantly lower in comparison with those of the control group.
Conclusion: The results of our study demonstrated that using probiotic supplements in women with GDM had beneficial effects on glycemic control, reduction of the requirement of using insulin, serum LDL cholesterol concentration, serum HDL cholesterol concentration, and less adverse pregnancy and infancy outcomes
Sahar Avazpour, Javad Nemati, Mohammad Hemmatinafar, Mohsen Salesi,
Volume 45, Issue 4 (12-2021)
Abstract
Background and Aim: Reduction of any mobility and activity can cause many diseases as cardiovascular diseases. The aim of the present study was investigation of the effect of a combined training period (aerobic and High Intensity Interval Training) and high intensity interval training on Homocysteine and ESR in cardiovascular patients.
Materials and Methods: In the current experimental study, 32 cardiovascular patients were selected voluntarily and were randomly divided into 3 groups: combined training group (n = 10), HIIT training group (n=11), and control group (n = 11). Inclusion criteria included injection fraction greater than 30, lack of tachycardia and bradycardia, and lack of functional capacity less than 5 met, and the exclusion criteria included unwillingness to continue the activity and diagnosis by a physician. The protocol of the HIIT training group included performing 2-3 times a week of HIIT training during the first 4 weeks and performing 3 times a week of HIIT training during the second 4 weeks.
Blood samples were taken 24 hours before the first training session and 48 hours after the last training session, under the same conditions for all the three groups. Data analysis was performed using paired sample t-test, ANOVA, and post hoc with a significance level set at P˂0.05.
Results: The performing of combined exercises and HIIT was found to have a significant effect on reducing serum homocysteine levels (combined exercise (baseline values of 19.7± 1.3, after intervention 13.8 ± 2.3, P˂0/00), HIIT exercise (baseline values: 20.0± 1.3, after intervention: 16.3± 1.5, P˂0/001)) and ESR levels (combined exercise (baseline values: 27.7 ± 2.1, after intervention: 22.13 ± 1.27, P˂0/005), HIIT exercise (baseline values: 26.2 ± 2.8, after intervention: 22.9 ±2.0, P˂0/004)) compared with the control group (Homocysteine P˂0/619, ESR P˂0/306) of cardiovascular patients.
Conclusion: Combined and HIIT trainings seem to be effective in reducing homocysteine and ESR in cardiovascular patients, while the effect of combined exercise is greater than that of HIIT.
Hatam Ahmadi, Homiera Homihatami Nemati, Reza Shahbazi Ilekhchi2, Hosieni Hosieni, Faezehe Zogoulipour,
Volume 46, Issue 1 (4-2022)
Abstract
Background and Aim: Methamphetamine is known as a nerve stimulant and addictive substance.Prerequisite for methamphetamine-induced behaviors is the effect of the drug on the relevant genes and proteins mentioned in the previous studies. Here, we made an attempt to examine the effect of
intraperitoneal injection of this drug on the expression of specific genes AKT, GSK3b, BDNF, and CREB in the lumbar spinal cord.
Methods and materials: In the current experimental study, we examined the effect of five days of intraperitoneal injection of methamphetamine and its withdrawal on increasing the reaction time of the tail in response to the shock of burning light and shook and alterations in the expression of
specific genes in comparison with the sequence relevant primers in the lumbar spinal cord of four experimental groups (each including 7 male rats). For data analysis, one-way ANOVA was run in SPSS.
Results: Intraperitoneal injection of 10 mg/kg methamphetamine over a five-day period, by increasing the reaction time of the animal's tail to the shock of burning light from 3.17 to 6.8.8 seconds, induced analgesia (P-<0.01) and increased the expression of Protein kinase B (AKT) and cAMP response element-binding protein (CREB) genes in the lumbar spinal cord of male rats (P <0.05 and P<0.01, respectively), whereas it did not significantly alter the expression of Glycogen synthase kinase3 (GSK3b) and Brain-Derived Neurotrophic Factor (BDNF) genes in this region (P =0.2 and P=1, respectively). Also, deprivation of methamphetamine in the drug deprivation group, by reducing the tail reaction time from 6.88 seconds to 3.9 seconds, reduced the analgesic effect of the drug (P <0.01), but the expression of the mentioned genes in this group did not change significantly as compared with the methamphetamine group.
Conclusions:It seems that the intraperitoneal injection of methamphetamine dose over a short period of time has only a beneficial analgesic effect and its minimal effect on changes in gene expression is not sufficient to be interpreted as drug abuse and induce addiction.
Sahar Avazpour, Javad Nemati, Majid Dejbakht,
Volume 46, Issue 2 (6-2022)
Abstract
Background and Aim: Immobility and movement restrictions are the cause of many diseases, including cardiovascular disease. Cardiovascular diseases are among the diseases related to inactivity and the main cause of death in the world. One of the main factors in the prevention and treatment of these diseases is to do sports activities. Since choosing the right exercise program for these patients is of great importance and limited researches have been done in this field; Therefore, the aim of this research was to investigate the effect of a period combined and intermittent exercises on the levels of C-reactive protein and galectin in cardiac patients.
Methods: During this clinical trial, 36 cardiovascular patients (with an average age of 55.14±1.4, weight 78.6±5.1 and body mass index 27.81±33) were voluntarily selected and after matching, the sample were placed in 3 groups: combined training group (n=13), interval training group (n=12) and control group (n=11). Inclusion criteria included lack of functional capacity less than 5 met, not having tachycardia and bradycardia and injection fraction was higher than 30. Exit criteria also included doctor's diagnosis and unwillingness to continue the activity. The protocol of the combined training group included performing aerobic continuous training 2-3 times a week without performing interval training during the first 4 weeks, then performing aerobic continuous training 2 times a week and performing intermittent training once a week during the second 4 weeks. The protocol of the interval training group included performing interval training 2-3 times a week during the first 4 weeks and performing interval training 3 times a week during the second 4 weeks. Blood samples were taken 24 hours before the first training session and 48 hours after the last training session (in the same conditions for all three groups). Data analysis was done using dependent t statistical program, covariance (ANCOVA) and Post Hoc (Sheffe test) at a significance level of P<0.05.
Results: Findings: The implementation of combined exercises and interval training has a significant effect on the reduction of C-reactive protein serum levels in combined exercise by 1.59 ± 0.11, P˂0.05, in interval training by 1.03 ± 0.08, P˂0.001 showed. Also, the number of changes in galectin-3 in combined training was 4.51 ± 0.28, P˂0.005, in intermittent training it was 2.32 ± 0.14, P˂0.004 compared to the control group with values of 0/034 ± 0/002, P˂0/316 was observed. In inter-group comparison with analysis of covariance, the inter-group changes for C-reactive protein were 1.38 ± 0.15, P˂0.001 and for galectin-3 it was 1.05 ± 0.11, P˂0.001.
Conclusion: It is likely that combined exercises and intermittent exercise are effective in reducing the serum levels of C-reactive protein and galectin-3 in cardiovascular patients, and causes a further decrease in the levels of these two inflammatory indicators (high levels of which are a sign of cardiovascular diseases). As a result, according to the specific results, it is likely that combined training is more effective in reducing the risk factors of heart disease than intermittent training. And it can be prescribed to improve the health of heart patients.
