other گزارش چهار مورد استئوژنزامپرفکتا بین رشته ای ( مدیریت آموزشی، تحقیقات آموزشی، آموزش پزشکی ) Interdisciplinary (Educational Management, Educational research, Statistics, Medical education پژوهشی Original <div style="text-align: justify;">نشانگان بیماری با استئوژنزامپرفکتای مادر زادی مطابقت دارد. وجود صلیبه آبی، با توجه به آمارهای موجود، درصد درصد موارد دیده نشده است. عدم وجود نشانگان بیماری در والدین شاید موید ابن نوع کلینیک بیماری باشد.</div> <div style="text-align: justify;">Four cases of osteogenesis imperfecta along with clinical and laboratory studies were reported.&nbsp;<br> Autosomal dominant pattern of transmission was most pro - bable in the first case owing to the fact that all members of the family showed blue sebera,two third was affected with various fractures and one forth suffered with deafness.&nbsp;<br> Recessive abnormal trait probably due to new mutation was the case for our second patient since no pertinent phenoty&shy;picity was disclosed in the parents;although it could also be caused by autosomal dominant transmission with low expre&shy;ssity in parents giving rise to congenital form of the disease.&nbsp;<br> Our thir􀁆 case without any evidence of disease in the parents was co􀁈sidered as a recessive genetic transmission, although it might be envisaged as a dominant genetic trans&shy;mission with early appearing sympthomatology.&nbsp;<br> O.I.in our fourth case with normal appearing parents was consistent with recessive way of transmission.<br> Mental retardation without any proved acquired etiology in the first case in association with O.I.was of interest, requiring further investigations.</div> 102 122 http://pejouhesh.sbmu.ac.ir/browse.php?a_code=A-10-3973-366&slc_lang=other&sid=1 Ahmad Bahvad احمد بهواد 100319475328460020821 100319475328460020821 Yes Mahnaz Aala Nour مهناز اعلا نور 100319475328460020822 100319475328460020822 No گروه کودکان بیمارستان شماره 4 بیمه های اجتماعی وابسته به دانشگاه ملی ایران.