School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Verrucocus Carcinoma of Uterine Cervix 0 0 OTHER Mohsen Ariazad Department of Pathology, Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammadreza Raffei Department of Pathology, Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Jafar Nasohi Department of Maternity, Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mehrangiz Khatami Department of Maternity, Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammad Hasan Kareemi Nejad Department of Pathology and Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Verrucous carcinoma is a peculiar type of squamous cell carcinoma character­ized by a clinicopathological behavior.This neoplasm is grossly cauliflower, warty, or parachute in shape, slowly growing and pushing the adjucent tissue without a definite invasion. Rarely causing metastasis. This tumor is radio­resistant and the choice treatment is surgery. Histological features resemble the papilloma and is easily misdiagnosed as a benign lesion. Clinicians and pathologists should be alert and correlate clinicohistological findings in order to make a proper diagnosis. A case of verrucous carcinoma of cervix is being reported and literatures are briefly reviewed. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Report of a Case Report of Kindler Syndrome 0 0 OTHER Parviz Toosi Department of Dermatology, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Shoora Mani Ghalam Department of Dermatology, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. A 13 years old boy with progressive poikiloderma, bullous lesions in the extremities and photosensitivity is reported. Physical examinations were otherwise normal, his physical development was normal, no other family member had a similar disease. Routin laboratory exams were in the normal limits.Histopathology exams from poikilodermatous skin showed atrophy of the epidermis, liquification degeneration of basal lyer and increase in melanin pigment in that area. Biopsy from bullous lesions showed a subepidermal bulla. Poikiloderma is a rare skin sign and when it occurs early in life usually is a sign of a hereditary and congenital disease. Bullous lesions in the extremities which are probably related to the trauma suggest diagnosis of epidermolysis bullousa. Association of the above two signs under the title of Kindler Syndrome was reported by the T. Kindler un 1954 for the fir st time. As far as we 􀁇w this is the first case of Kindler Syndrome which is reported in Iran.

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Evaluation of 27 Cases of Uretero Pelvic Junction Stenosis 0 0 OTHER Manochehr Amir Faiz Department of Pediatrics Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Jafar Kooranlou Department of Pediatrics Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mahmoud Seyed Asadi Department of Pediatrics Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Yasaman Abtahi Faculty of Nutrition Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. We reviewed our management of children with uretero pelvic Junction stenosis due to various pathology in a series of 30 Hydronephrotic kidneys in 27child­ren from 1359 till 1365 in pediatric Surgery Ward to Taleghany Medical Center. The common presenting feature is abdominal mass up to one year age and loin or abdominal pain nucturia was the most frequent complain in older children. The conditions was more common in the male than in female and occured more frequently on the left side. It was common bilaterally in infants.The incide­nce of urinary infection was low and only 1 patient was hypertensive. Dis­membered pyeloureteroplasty was the procedure of choice for reconstruction preliminary nephrostomy performed in 4 patients and nephrostomy was done in the late results assessed clinically and 2 patients radiologically have been entirely satisfactory. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Dietary Iron Intake in Relation to Nutritional Anaemia Among Young Iranian Boys and Girls. 78 81 OTHER Aminpour Institute of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Ferdosian Institute of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Fifty young students, 39 females and 21 males with the Mean ages of 19 - 23 years, were studied to determine if hemoglobin and serum iron differences existed between the two groups and if so whether they were due to dissimilar nutrient intakes. Each subject kept a four day dietary diary and provided a fasting blood sample on the last day of the diary recording. The energy , protein and iron intakes were calculated from the local food composition table.The Mean Rb of women and men were respectively 13.7 ± 1.67 and 14.8±1.32 g/100 and serum iron level were 68.5 and 82.2 mg/100 ml. The Rb and serum iron levels of females were significantly lower than the males. The average energy, protein and iron intakes of women were also showed low­er consumption comparing with men. 54 percent of the females had iron intake lower than the RDA (16-18 mg/day). There was a statistical significant posi­tive correlation between the energy and iron intake. Therefore the low iron intake among the young females could be considered as a consequence of a decrease in their daily energy intake. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Measurment of The Width of Subcutaneous Adipose Tissue in Tehranian Children of 7 to 11 Years of Age (1359-1361) 82 96 OTHER Nayer Rasaian Depatment of Physiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Effat Barghi Depatment of Physiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Behrooz Katoozian Deptment of Hygiene, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammad Danesh Pajouh Deptment of Cardiovascular Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran. As a result of the previous studies it was obvious that weight alone or even weight relative to height is an inadequate measure of fatness, so fatfolddata including both triceps and subscapular fatfolds for about 3912school girls and boys have been studied during a survey about blood pressure standards and cardiovascular diseases in school children of Tehran. The results show a significant increase in girls skinfold rather than boys and give rise with age in both sexes. The correlation coefficient of skinfold relates directly to age, weight, BMI and systolic and diastolic ( K4, K5) pressures and indirectly to PI in both sexes. The correlation coefficient of triceps fatfold relates indirectly to birth-order and family size and direct­ly to their dwelling rooms. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Serum Concentrations of Various Hormones Following Exposure to Chemical Weapons Containing Sulfur Mustard 97 101 OTHER Fereydoun Azizi Faculty of Medicine, Shahid Beheshti University of Medcal Sciences,Tehran,Iran. Hossein Elyasi Faculty of Medicine, Shahid Beheshti University of Medcal Sciences,Tehran,Iran. Hamid Sohrabpour Faculty of Medicine, Shahid Beheshti University of Medcal Sciences,Tehran,Iran. Naser Jalali Faculty of Medicine, Shahid Beheshti University of Medcal Sciences,Tehran,Iran. Mahtalaat Nafarabaci Faculty of Medicine, Shahid Beheshti University of Medcal Sciences,Tehran,Iran. Serum concentration of FSH, LH, testosterone, prolactin,ACTH,cortisol, TSH, T ,T and resin Tuptake were measured in 146 men who were exposed to vesicants used by Iraqi regime, few days to 4 weeks prior to test'ing, Clinical and laboratory findings had confirmed that mustards had been used. Mean serum concentrations of FSH, LH, TSH and prolactin were not signi­ficantly different from normals. Free Tindex (FTI) was ·subnormal in 6 men, 4 and its mean was somewhat decreased (7 .4 ± 0.8 vs; normal 8. 7 ± 1. 2;P""- 0.05). Free Tindex (FTI) was subnormal in 14 men, and its mean was significantlylower than normal (92±20 vs 130±11; P < 0.001). Serum testosterone concentration was subnormal in 42 men, and its mean was significantly lower than normal (361 ± 254 vs 676 ± 273 ng/dl; P..( 0.001). Serum cortisol, was subnormal in 11 and above normal in 8 men, its mean was not significantly different from normal values. There was an increase in serum ACTH concentration. We conclude that exposure to chemical weapons containing mustards may cause sever alterations in serum concentrations of various hormones. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Evaluation of Tinea-Versicolor Disease 102 107 OTHER Mahin Moghadami Department of Medical Mycology, School of Public Health, Tehran University of Medcal Sciences,Tehran,Iran. In a survey during a period of 2 years, 1084 patients with suspected clinical fungal lesions were referred to the Medical Mycology Department, School of Public Health of Tehran Medical Sciences University. Out of 1084 patients , 329 cases were found to be infested with Tinea versicolor. One (0.3%) conju­gal case and 2 (0.6%) blood related cases (Father and son, Mother and daugh­ter) and 4 cases (1.2%) concomitant lesion of Tinea versicolor and Erythrasma in the groin and 2 cases concomitant Tinea versicolor and Dermatophytosis of the face and groin were observed. Males 190 cases (57. 7%) were affected more than females and the most of the patients were between 20-45 year old and the Trunk (62.31%) was the most common area which was affected. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Evaluation of Four Patients with Porokeratosis of Mibelli 108 111 OTHER Mohammad Jafar Mooayyed Department of Dermatology, Modarres Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. We describe the clinical and pathologic observation of four patients with Porokeratosis of Mibelli. Allof them were women. They had four different forms of disease: Plaque type, functate form, Linear form and superficial disseminated form. In histologic features we observed a new change in basement membrane of epidermis in two patients. This change composed of Liquefaction degeneration of basal membrane, which this change has not reported in any literature. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Generation and Evaluation of Monoclonal Autoantibodies in Systemic Lupus Erythematosis 122 131 OTHER Robabeh Rezaei Poor Department of Microbiology and Immunology, Faculty of Mecicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Three murine monoclonal anti-ssDNA autoantibodies have been produced by fusion of spleen cells from NZB/NZW F1 hybrid mice with Sp2/0-Ag 14 murine myeloma cells. Specificity studies characterizing monoclonal anti - ssDNA autoantibodies revealed binding patterns for nucleotides. Clone E-4-1 showed preferential binding with mono-di-and polyguanosine. Clones E-4-4 and E-11-1 specitically bound mono-di-and polythymidine. Results of inhibition studies indicated an order of reactivity for each monoclonal autoantiby; polynucleotide) dinucleotide) mononucleotide. 

School of Medicine, Shahid Beheshti University of Medical Sciences Research in Medicine 1735-5311 11 3 1987 9 1 Prophylactic Radiotherapy in Acute Lymphocytics Leukemia of Children 132 136 OTHER Asadollah Alidoosti The concept of CNS preventive therapy in childhood all is based on the assumption that undetectable CNS leukemia is present in most patients at the time of diagnosis, residing in that "sdnctuary site" protected by the blood-brain barrier from cytotoxic concentrations of most systemically ad­ministered antileukemic agents. Studies in the 1960s demonstrated that administration of 2400 rad cranial irradiation and intrathecal me thotrexate following systemic remission induc­tion reduced the incidence of overt CNS leukemia to, approximately 10% or less,which called CNS prophylaxis. There is now a large body of data that indicates that significant long-term side-effects, including impaired in - tellectual and psychomotor function, and neuro-endocrine dysfunction, may occur in patients treated with 2400 rad cranial irradiation. These findings have stimulated a search for alternative methods of CNS preventive therapy. It is now apparent that the risk of developing CNS leukemia varies in different patient depending upon a variety of predictive factors ( high initial WBC count, T-cell disease, thrombocytopenia, profound lymphadenopathy, or hepatosplenomegaly). Studies suggest that 1800 rad is as effective as 2400 rad, without sac - rificing control of CNS leukemia. So, for determination of the dose of irra­diation, we must look the age of the patient and the clinical features at presentation. Meanwhile, cranial irradiation and intrathecal methotrexate remain the best established way to prevent this chronic and distressing com­plication of childhood leukaemia.