Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Abstract: (2067 Views)
Four year old girl was evaluated for precocious puberty. Breast development and pubic hair growth had started at age 2½ year, and had been followed by vaginal bleeding resembling periods. Gaf-au-lait spots were present in most of her skin surface. Bone x-rays showed multiple cysts in pelvis and the metaphysis of femur. Diagnosis of McCune-Albright syndrome was made. Concentrations of all hormones were within normal limits. Treatment with medroxyprogesterone and cyproterone acetate, in separate occasions, was successful.