Volume 38, Issue 4 (1-2015)                   Research in Medicine 2015, 38(4): 187-192 | Back to browse issues page

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Nouri S, Sharif M R, Panahi Y, Ghanei M, Jamali B. Investigating the effect of calcium sulfate on liver hemorrhage control in an animal model . Research in Medicine. 2015; 38 (4) :187-192
URL: http://pejouhesh.sbmu.ac.ir/article-1-1245-en.html
Trauma Research Center, Kashan University of Medical Sciences , dr.mrsharif@yahoo.com
Abstract:   (4902 Views)

Background: The control of parenchymal hemorrhage especially in liver parenchyma, despite surgical science progresses is still one of the challenges surgeons face saving the patients’ lives and there is a research challenge between the researchers in this field to introduce a more effective method. This study aimed to determine the hemostatic effect of calcium sulfate on controlling the bleeding from liver parenchymal tissue. Materials and methods: In this animal model study 60 male Wistar rats were used. A length of two cm and a depth of half a cm incision were made on each mouse’s liver and the hemostasis time was measured using calcium sulfate different concentrations (5%, 10%, 15%, 25%, and 50%) and the control method (i.e. control of bleeding by suturing). Finally, the obtained data were entered into SPSS software and analyzed using Kruskal-Wallis test and Mann-Whitney, Kolmogorov-Smirnov. Results: The hemostasis time of calcium sulfate concentration groups was significantly less than that of the control group (p<0.01). Conclusion: Calcium sulfate is an effective hemostatic agent in controlling liver parenchymal tissue hemorrhage in an animal model.

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Type of Study: Original | Subject: Surgery
Received: 2014/04/26 | Accepted: 2015/06/22 | Published: 2015/07/8

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