Research in Medicine

Background: It has been suggested that local endometrial injury (LEI) can increase the success rate of assistive reproductive technologies. Previous studies have been resulted in controversial diseases. In current study, we investigated the effect of LEI on the rate of clinical pregnancy and live birth in women undergoing frozen embryo transfer (FET).

Materials and Methods: There were 120 infertile women assigned to two equal groups, randomly: LEI group and control group. Patients underwent FET procedure. The rate of clinical pregnancy and live birth were compared between two groups.

Findings: The rate of clinical pregnancy was the same (35% in LEI group versus 33.3% in control group; p<0.05). Also, the rate of live birth did not significantly differed between two groups (23.3% in LEI group versus 21.6% in control group; p<0.05).

Conclusion: Based on our findings, LEI does not improve the rate of clinical pregnancy and live birth in women undergoing FET.