One of the most important advances in imsulin therapy has been the commercial production of highly purified single peak and single component insulin. The routine use of these pre9ara -tions have reduced insulin allergy and abolished insulin lipoatrophy.
The subject of low dose insulin infusion in diabetic keto - acidosis in still controversial,but is based on sound theoreti - cal and experimental basis and offers advantages over the ciassic method. We believe that its routine use should be allowed only under expert supervision. Artificial pancreas is on its way for routine application in treatment of acute conditions in hospitalized patients and in diabetic coma. Chronic use of artificial pancreas for management of diabetic patients has to wait for further technical advances.