Showing 3 results for madani
Manochehr Amirfeyz, Jafar Koranloo, Mirmohammad Seyed-Ahadi, Abdollah Aale-Agha, Abbas Madani,
Volume 10, Issue 3 (March 1986)
Abstract
During a period of two years (1984 - 1985), three patients with diagnosis of choledocal cyst have gone under operation in department of pediatric surgery (Taleghani Medical Centre). Choledochal cyst is a congenital malformation of the pancreatobiliary system. Its pathogenesis is not yet completely understood.The famale/male predisposition is 4/1. More than 50% of the patients present during their first decade of life. The classic triad are abdominal pain, jaundice and abdominal mass. Ultrasonography is the best initial method of im·estigation of choledochal cyst. Abdominal Ct scan and percutaneus transhepatic cholangiography and ERCP can also be helpful in finding unsuspected biliary cyst. Operathe cholangiography is recommended in all types of choledochal cyst. Operative resection of choledochal cyst and gallbladder with biliary reconstruction by ROUX - EN - Y choledochojejunostomy is the treatment of choice. Primary excision of the cyst is mandatory to prevent ascending cholangitis and development of carcinoma.
Sareh Beigom Madani, Kumarss Madani,
Volume 42, Issue 1 (3-2018)
Abstract
Background: The most important factor in the formation of Staphylococcus aureus is the ability to form biofilms. This bacterium has the ability to bind and penetrate into tissue cells. Biofilmic infections are usually chronic and reversible and respond to difficult treatments. The purpose of the present study was to
identify biofilm genes in Staphylococcus aureus isolated from clinical and food samples using multiple PCR methods.
Materials and Methods: A total of 60 isolates of Staphylococcus aureus, cultured from human and food after extraction of genome, were used to study the presence of adherent genes using multiple PCR techniques. The phenotypic study of biofilm formation was performed using Microtiter plates assay microplate technique.
Results: In total, 60 human and food samples were studied that included 6 samples of foodstuff, 20% of samples and of 2 samples clinical 6.67% isolated from biofilms. In 30 isolates isolated from food, the frequencies of fnbB, clfB, and clfA genes were identified as 20%, 76.66%, 80%, respectively. However, among the 30 clinical samples, the frequencies of fnbB, clfB, and clfA genes were 6.66%, 70%, and 93.33%, respectively. The fnbA gene was not detected in any of the samples.
Conclusion: The results of the study showed that the high prevalence of biofilm-inducing genes and also a relatively high phenotypic expression among the samples showed that it could be related to the resistance of the isolates of Staphylococcus aureus.
Saeid Bahrami, Sogol Kianersi, Atefeh Solouk, Hoda Madani,
Volume 43, Issue 2 (7-2019)
Abstract
Background: In spite of promising results of conventional treatments for myocardial infarction, including
medications, stent implantation, and coronary artery bypass grafting, the disease and its complications,
especially heart failure, are highly prevalent because these methods could not reverse the cell loss, which
is the main problem. Currently, heart transplantation, as the last option for treatment of heart failure, has
major limitations including the low number of appropriate donors and underlying diseases in recipients.
Materials and Methods: The present study is presented as a review paper. Using related keywords, including
myocardial infarction, cell therapy, stem cell, cardiac tissue engineering, and clinical trials, studies published
up to 2018 were collected from reliable databases, including Google Scholar, PubMed, Scopus, and Elsevier.
Among potential candidates, those which were the most relevant to the purposes of the study were selected
and evaluated.
Results: The stem cells application for regeneration of damaged tissues is one of the great researchers’
achievements. In spite of various scientific, legal, and ethical concerns, several companies target stem cells
transplantation for cardiac diseases in commercial way. There are many in situ, in vitro, and cell-loaded
scaffold and cell sheet engineering studies in tissue engineering field.
Conclusion: Despite the promising results of stem cells application, many challenges still lay ahead of this
pathway including optimal cell, dosage, time and route administration selection, and the immune response
modulations. Currently, extensive research is ongoing. In this regard, the successful results of various clinical
trials made by different companies and health centers have led to commercialization of products. Some of
them are addressed in the current review article. However, more research is needed to clarify the efficacy of
these studies.
