Showing 2 results for Disinfectants
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Volume 37, Issue 4 (2-2014)
Abstract
Abstract Background: Excessive consumption of antimicrobial materials in hospitals and the community is as the main encoder, led to the emergence, development and acquisition of new bacterial resistance to antimicrobials. According to the lack of enough information about the mechanisms of the resistant genes to disinfectants and receiving no report from the country and considering the resistance or sensitivity of the isolates of the Acinetobacter baumannii MDR in facing disinfectants, this study was taken place in the selected intensive care units if the hospitals of Tehran. Materials and methods: This experimental study which was conducted over a period of 10 months, Acinetobacter baumannii species were separated by culture and biochemical tests. The resistance and sensitivity of the isolates to antibiotics is considered according to CLSI (2012) guidelines. By multiplex PCR method blaCTX and blaTEM were detected and finally, MDR strains were treated with 2% glutaraldehyde. Results: Of 588 samples, 131 isolates (22.28%) of Acinetobacter baumannii were isolated. The amount of the resistance to various antibiotics was in the range of the 69.4% to 100%. The frequencies of the blaTEM and blaCTX were 3.2% and 19.4%, respectively, and there was no resistance to glutaraldehyde. Conclusion: It seems that beside variety and prevalence of blaTEM and blaCTX, enormous mechanisms like porin and leaking systems (efflux Pumps) are responsible in the making of the resistance of Acinetobacter baumannii to disinfectants. Also these results facilitated the study of phenotypic and genotypic resistance patterns of these antimicrobials and disinfectants in different parts of the world. Keywords: Acinetobacter baumannii, Lactamase genes, Disinfectants, Antimicrobial resistance.
Dr Fariba Balouch, Mr Mehdi Mohammadi, Dr Shahram Behboudi,
Volume 45, Issue 3 (9-2021)
Abstract
Background: Considering the prevalence of color changing of shade guides resulting from the use of disinfectants, the aim of the present study was to evaluate the effect of two disinfectants Desomed and Deconnex +53 on Vitapan shade guide.
Methods and materials: The present experimental–in vitro study was conducted on a total of 30 A2 shade tabs. In the case group, 10 samples were merged in each of disinfectants and 10 sample were placed into distilled water as control group. Color selecting process was performed for 5 days, 3 times a day, by dentist. After 480 repeated cycles of this procedure, according to CIELab system, primary color of 10 samples were measured using Konica Minolta spectrophotometer as the control group. Also, color indices were measured making using of Vident spectrophotometer in the CIELAB system. Statistical analyses were performed running Two-way ANOVA.
Results: The rate of color change indices showed that the color changing (ΔE) indices for Deconex+53 and Desomed were 1.23∓0.55 and 3.69∓1.3, respectively. Thus, the ΔE of Desomed was twice more than that of Deconex +53. Our results revealed that the discoloration of Desomed was statically
significant and higher than that of Deconex (p<0.001).
Conclusions: It can be concluded that Desomed has more color changes compared with Deconex in similar conditions.
