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Showing 4 results for Thyroxine
The Therapeutic Effect of Thyroxine in Reducing the Size of Cold Knots of Thyroid
Fereydoun Azizi, Masoumeh Miresmaeili, Maryam Azizi,
Volume 14, Issue 1 (3-1990)
Abstract
There is no English abstract.
The Effect of Bromocriptine on the Secretion of Hypophysial Thyroidal Hormonal Axis
Masoud Amini, Mehrdad Hosseinpour,
Volume 23, Issue 1 (3-1999)
Abstract
Thyrotropine secretion in human beings is under the influence of various factors. The effect of the hormones, triiodothyronine, thyroxine, somatostatin and thyroid-stimulating hormone has been well known. In this study the direct effect of stimulation of the dopaminergic system by bromocriptine on the thyrotropine secretion was investigated.
In this study twenty women with hyperprolactinemia referred to the endocrine and metabolism research center of the Isfahan University of Medical Sciences were selected. For this purpose, only cases with prolactin levels greater than 20 nanogram were included in the study. The cases suspicious of systemic diseases and consumption of thyroid stimulatory drugs were excluded from the study. Five milliliter of blood was collected from each patient and then they were appropriately treated by bromocriptine. After 3 months their bloods were again collected. The levels of thyroxine, triiodothyronine, thyrotropine and prolactin were measured by the radioimmunoassay method.
Thyrotropine levels showed a significant decrease (2.95 ± 0.89 mU/l before and 1.85 ± 1.08 mU/l after treatment) (P<0.001). In addition, the prolactin levels showed a significant decrease (30.08 ± 13.2 ng/ml before and 3.5 ± 2.2 ng/ml after treatment) (P<0.007).
A significant relationship was found between decreases for TSH and triiodothyronine (r =+0.49, P<0.05) and between decreases for prolactin and TSH (r = +0.47, P<0.05).
It can be concluded that the stimulatory effect of bromocriptine on the dopaminergic system can decrease the bodily levels of thyroid hormones through affecting the secretion rate of TSH.

The high prevalence of severe congenital hypothyroidism: A necessity for an effective strategy of detection and treatment in the national screening program for neonatal hypothyroidism
Ordookhani A, Mirmiran P, Hedayati M, Ramezankhani A, Azizi F , , , , ,
Volume 28, Issue 1 (3-2004)
Abstract

Background: Streptococcal pharyngitis is the most common type of acute bacterial pharyngitis that may  have different complications if remained untreated. On the other hand, antibiotics may impose side effects if  prescribed for healthy subjects, thus, the appropriate diagnosis of affected individuals is of utmost importance. Previous studies have indicated the accuracy of Rapid Test for streptococcal pharyngitis, so the present study was conducted to determine the accuracy of Rapid Test among a group of Iranians.

Materials and methods: For this clinical trail, 320 consecutive cases of sore throat were enrolled. Rapid  Test was performed for all cases however, culture was our gold standard for diagnosis. Finally, positive  predictive value and negative predictive value were calculated.

Results: The study population included 150 males and 170 females with the mean age of 21±7 years. The  positive and negative predictive values of Rapid test were 66% and 98.5%, respectively.

Conclusion: With respect to the known complications of acute pharyngitis, we strongly recommend Rapis  test for all patients with sore throat.


Content Analysis of of Chinese herbal pills for weight loss
Marjan Khazan, Mehdi Hedayat, Sahar Askari, Fereidoun Aziz,
Volume 35, Issue 4 (2-2012)
Abstract
Abstract Background: Chinese herbal products for weight loss are popular in Iran and other countries of Asia. We have investigated the content of some of these products present in Iranian markets. Methods: Nine different types of herbal pills used for weight loss were obtained from open market and subjected to qualitative analysis. Immuno-chromatographic assays for the detection of phencyclidine and radioimmunoassay methods for thyroid hormones (T3 & T4) were employed. Results: No natural ingredient was present in the herbal slimming pills. All products except three contained triiodothyronine(T3). Magic Slim and 100% Original Super Slim carried thyroxine (T4), 10 microgram per pill and 63 microgram per pill respectively. Phencyclidine was found in herbaceous essence, Green Lean, Super Slim and Fat loss. Conclusion: Chinese herbal products must be evaluated for their safety before marketing. Manufacturers should be licensed by regulatory agency and manufactured under good manufacturing practice. Proper labeling and good surveillance systems shall ensure the protection of the consumers. Keywords: Chinese herbal pills, Immunochromatographic, Thyroxine, Triiodothyronine, Phencyclidine, Weight loss.
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