Mr. Akbar Moein, Dr. Hojatolah Nikbakht, Dr. Farshad Ghazalian,
Volume 41, Issue 3 (9-2017)
Abstract
Background: The present study aimed to examine the effect of aerobic training on Klotho protein, interleukin-6 and tumor necrosis factor alpha inflammatory factors in rats.
Materials and Methods: For this purpose 12 male rats with an average weight 170g±5g and the age of eight weeks were divided into two groups: control (N= 6) and experimental (N= 6) groups. The experimental groups trained on a treadmill for 8 weeks and 3 sessions per week. 48 h after last training session, both groups of rats were slaughtered ethically and kidney tissue were extracted. Klotho, IL-6 and TNF-α proteins of kidney tissues were measured and counted using by western blot method.
Results: The Klotho protein (P = 0/05) significantly increased in trained rats compared with the control group. Also the IL-6 protein (P = 0/05) significantly decreased in trained rats compared with the control group. While the TNF-α protein (P = 0/42) did not show a significant difference.
Conclusion: aerobic training might increase the Klotho protein, on the other hand can also decrease the levels of IL-6 protein secreted by kidney. So it can be said that probably aerobic training may delay aging symptoms and may decrease in inflammatory responses.
Keywords: Aerobic training, Klotho, TNF-α, IL6
Ms Fatemeh Nejati, Dr Nahid Bijeh, Dr Mahtab Moazami,
Volume 43, Issue 3 (10-2019)
Abstract
Background:Cardiac diseases are the main cause of 50% of death post menopause. The purpose of the present study was to determine the effect of water aerobic training with and without green tea on some cardiovascular risk factors and body composition of sedentary postmenopausal women conducted at Ferdowsi University of Mashhad in 2012.
Materials and Methods: In the present experimental study, a total of 30 sedentary postmenopausal women with the mean age of 57.03±6.62 years were randomly divided into three groups (aerobic exercise in water, green tea, exercise + green tea). The aerobic exercise in water program for the exercise group and the exercise group + green tea was eight weeks with a frequency of three sessions per week with an intensity of 55-70% of maximal heart rate. Green tea and exercise groups + Green tea consumed six grams of dried green tea powder daily in three meals. Data were analyzed using dependent sample t-test and one-way ANOVA at a significance level of P<0.05.
Results: The results of the study showed that eight weeks of interventional intervention could not change the liposomal and tonicity indices. However, aerobic power increased in all three groups, while intergroup changes were not meaningful.
Conclusion: Aerobic exercise in water for eight weeks alone and along with the use of green tea did not have an effect on the improvement of benign and lipid indices in active postmenopausal women, while increasing their aerobic capacity.
Sahar Avazpour, Javad Nemati, Majid Dejbakht,
Volume 46, Issue 2 (6-2022)
Abstract
Background and Aim: Immobility and movement restrictions are the cause of many diseases, including cardiovascular disease. Cardiovascular diseases are among the diseases related to inactivity and the main cause of death in the world. One of the main factors in the prevention and treatment of these diseases is to do sports activities. Since choosing the right exercise program for these patients is of great importance and limited researches have been done in this field; Therefore, the aim of this research was to investigate the effect of a period combined and intermittent exercises on the levels of C-reactive protein and galectin in cardiac patients.
Methods: During this clinical trial, 36 cardiovascular patients (with an average age of 55.14±1.4, weight 78.6±5.1 and body mass index 27.81±33) were voluntarily selected and after matching, the sample were placed in 3 groups: combined training group (n=13), interval training group (n=12) and control group (n=11). Inclusion criteria included lack of functional capacity less than 5 met, not having tachycardia and bradycardia and injection fraction was higher than 30. Exit criteria also included doctor's diagnosis and unwillingness to continue the activity. The protocol of the combined training group included performing aerobic continuous training 2-3 times a week without performing interval training during the first 4 weeks, then performing aerobic continuous training 2 times a week and performing intermittent training once a week during the second 4 weeks. The protocol of the interval training group included performing interval training 2-3 times a week during the first 4 weeks and performing interval training 3 times a week during the second 4 weeks. Blood samples were taken 24 hours before the first training session and 48 hours after the last training session (in the same conditions for all three groups). Data analysis was done using dependent t statistical program, covariance (ANCOVA) and Post Hoc (Sheffe test) at a significance level of P<0.05.
Results: Findings: The implementation of combined exercises and interval training has a significant effect on the reduction of C-reactive protein serum levels in combined exercise by 1.59 ± 0.11, P˂0.05, in interval training by 1.03 ± 0.08, P˂0.001 showed. Also, the number of changes in galectin-3 in combined training was 4.51 ± 0.28, P˂0.005, in intermittent training it was 2.32 ± 0.14, P˂0.004 compared to the control group with values of 0/034 ± 0/002, P˂0/316 was observed. In inter-group comparison with analysis of covariance, the inter-group changes for C-reactive protein were 1.38 ± 0.15, P˂0.001 and for galectin-3 it was 1.05 ± 0.11, P˂0.001.
Conclusion: It is likely that combined exercises and intermittent exercise are effective in reducing the serum levels of C-reactive protein and galectin-3 in cardiovascular patients, and causes a further decrease in the levels of these two inflammatory indicators (high levels of which are a sign of cardiovascular diseases). As a result, according to the specific results, it is likely that combined training is more effective in reducing the risk factors of heart disease than intermittent training. And it can be prescribed to improve the health of heart patients.
