Volume 42, Issue 1 (3-2018)                   Research in Medicine 2018, 42(1): 34-39 | Back to browse issues page

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Kave Z, Ghorbani M. Evaluation of effecting factors on average glandular dose in mammography using MCNPX simulation code. Research in Medicine. 2018; 42 (1) :34-39
URL: http://pejouhesh.sbmu.ac.ir/article-1-1724-en.html
Abstract:   (3289 Views)

Background: Average glandular dose (AGD), entrance skin air kerma (ESAK) and normalized glandular dose (DgN) are the main dosimetric quantities in mammography. Breast tissue composition is one of the factors affecting on DgN values. In this study both homogeneous and heterogeneous breast tissue is assumed and its impact on DgN values are evaluated. Methods: Homogeneous breast phantom with different glandular fraction, was simulated and DgN values were calculated for the homogeneous phantom. Also a heterogeneous breast phantom was simulated that adipose tissue is in the background and glandular tissue is in the form of spheres that are in the breast phantom. By changing the radius of glandular tissue the glandular fraction in heterogeneous breast phantom was changed. DgN values were also calculated for the heterogeneous breast phantom. DgN values in both homogeneous and heterogeneous breast phantoms were compared and results were evaluated. Results: DgN values are depend on glandular fraction in both homogeneous and heterogeneous breast phantom. With the increased glandular fraction, DgN values are reduced almost linearly. Breast tissue heterogeneity is effected on DgN values, this effect is related to the distribution of the glandular tissue in the heterogeneous breast phantom. So that the change in the distribution of glandular tissue in the heterogeneous breast phantom, relative difference in DgN value between homogeneous and heterogeneous phantom is variable by -47 to +77 percent. Conclusions and Recommendations: In studies where DgN coefficients have been calculated, and this coefficients used in mammography dosimetry, has not considered the effect of heterogeneity of breast tissue. The results of this study and evident effect of heterogeneity glandular and fat tissue in the breast phantom, so a correction factor to the DgN values is recommended.

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Type of Study: General | Subject: Physics and Medical Engineering
Received: 2017/03/6 | Accepted: 2017/12/30 | Published: 2018/04/17

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