'rwo cases of post-partum amenorrhea with other clinical signs of She1ehan syndrom was studied at the Loghmandoleh Medical Center, National University of Iran.
Clinical diagnosis was confirmed by appropriate laboratory work -up in the f.irSlt case and the patient was placed on the conventional end orga.n hormon substitutional therapy (Thyroid -Gonad -Adrenal) and was discharged in good condition. She has been seen twice at our follow -up clinic since her discharge from the hospital in satisfactory condition.
In the second case despite presenting clinkal signs of Sheehan synd:rom pituitary response pattern to hy;pithalamic releasing factors (L.R.F'.) was show to be within normal limits and so did not confirm the clinical diagnosis.
Clinical manifestation in the second case was thought to be due to an advanced and uncontroled diabetes mellitus which was placed under appropriate treatment and left the hospital -in good condition.