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Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , chouhdariarezoo@gmail.com
Abstract:   (617 Views)
Objective: Opium use is a common cause of lead intoxication in Iran. This study was performed to determine the blood lead levels in oral and inhaled consumption of opium.
Methods and materials: This retrospective study between 1395 to 1396  was conducted on  200  patients with lead intoxication in  Loghman-Hakim Hospital. In this survey, patients' demographic information, type of opioid (oral or inhalable), blood lead levels and treatment outcomes were recorded and evaluated. For statistical analysis, independent t-test, one-way ANOVA and correlation coefficient were performed using spss software version 18.
Results: Based on the results, 97% of the patients were oral opium users. The mean (standard deviation) of blood lead levels in oral opium users was 108.86(34.29)  ppm and in inhaled type, 33.37(11.44) ppm. Significant correlation was found between the blood lead levels and age of the patients (r = 0.002, p=0.2). There was no significant statistical difference between the sexes, the method of opium use, the outcome of the patient and the serum level of lead (p >0.05) .
Conclusions: Based on the results, the mean blood lead levels in inhaled and oral opium consumption is closer toge also the understanding of public perception on the safety of inhalant use opium, suggested that programs to increase public awareness of the harms of inhaled use addition oral consumption , by administrators and health care providers is planned. As well as studies with more  inhaled opium users  to compare  blood levels of lead statistically in  two groups of oral and inhaled consumption should be done.  
 
     
Type of Study: Applicable | Subject: Toxicology
Received: 2019/10/14 | Accepted: 2020/10/19

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