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Department of Sport Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran , bashiri.jabbar@gmail.com
Abstract:   (652 Views)
Background and Aim: Due to the occurrence of various diseases due to inflammation, nowadays, finding a solution for inflammations caused by various factors is very important. Therefore, the aim of this study was to investigate the effect of 8 weeks of endurance training and complementation on the levels of CD22 and TRL4 in obese wistar rats. 
Materials and Methods: In the experimental study, 40 Wistar rats of two-month age range, were purchased from Pasteur Institute of Karaj and divided into four groups (each group of 10 animals) with high-fat diet without intervention, endurance training group and Only Olive Supplement and the Olive Supplement group with endurance training. Animals in the training groups performed a two-month endurance training program (80% maximal oxygen consumption). In the olive oil supplement group, one gram of olive oil per kg body weight was fed daily through oral gavage. ELISA method was used to evaluate serum TLR4 and CD22 levels and in Finally, Shapiro-Wilk test was used to evaluate the normal distribution of samples and one-way and two-way ANOVA was used for comparison between groups (p<0.05).
Results: The results showed that two months of endurance training alone don’t have a significant effect on inflammation )TLR4(P=0.09)، CD22(P=0.16)) in obese male Wistar rats. However, consumption of olive oil alone significantly reduced TLR4 (P = 0.009) and CD22 (P = 0.008), While two months of endurance training with oil consumption had no effect on TLR4 (P = 0.09) and CD22 (P = 0.10).
Conclusion: Therefore, according to the results of the present study, it seems that consumption of olive oil can reduce obesity-induced inflammation (TLR4) to some extent. However, further research is needed to fully reveal this.
     
Type of Study: Original | Subject: Physical Education and Sports Science ( Sport physiology- Sport biomecanic
Received: 2020/03/12 | Accepted: 2020/09/5

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