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Zahedan University of Medical sciences , Sharareh.sanei@gmail.com
Abstract:   (829 Views)
Background and Aim: Congenital anomalies are one of the leading causes of miscarriage, some of which can be detected before birth by ultrasound, screening and invasive tests such as amniocentesis and CVS. The aim of this study was to evaluate the possible complications of both CVS and amniocentesis in mothers with suspected chromosomal anomalies or major thalassemia.
Materials and Methods:  A descriptive-analytical study in which mothers, suspected of having a fetus with chromosomal abnormalities or major thalassemia, were referred to Ali Ibn Abitaleb Hospital in Zahedan, from October 2015 to October 2016 (150 mothers including 100 amniocentesis and 50  CVS). The mother had an ultrasound before the procedure, to assess gestatinal age, fetal health, placenta and amniotic fluid. After the procedure, each patient was followed for 14 days in case any complications such as vaginal bleeding, amniotic fluid leakage, miscarriage, PROM, and Chorioamnionitis occured. Data were entered into SPSS 18 software and analyzed by T and Fisher statistical tests.
Results: Observed complications include only amniotic fluid leakage and vaginal bleeding. Vaginal bleeding in CVS and amniocentesis group occurred respectively in two (4%) and one (1%) with P=0.465. Amniotic fluid leakage after CVS was seen in one case (2%) and after amniocentesis in two cases (2%) with P=0.632. No cases of miscarriage, PROM, and chorioamniovititis were observed.
Conclusion: This study shows that the complications of amniocentesis are not that different from CVS, and both methods can be used for prenatal diagnosis in high-risk pregnancies.
Type of Study: Original | Subject: Radiology
Received: 2020/05/13 | Accepted: 2020/10/4

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