Volume 36, Issue 3 (11-2012)                   Research in Medicine 2012, 36(3): 139-142 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Assadpour Piranfa M, Beyranvand M R, Fartookzadeh S, Valaei N. Relation between hs-CRP level and severity of coronary artery stenosis. Research in Medicine. 2012; 36 (3) :139-142
URL: http://pejouhesh.sbmu.ac.ir/article-1-1079-en.html
Department of Cardiology, Shahid Beheshti University of Medical sciences, Tehran, Iran , drpiranfar@yahoo.com
Abstract:   (7677 Views)
Abstract Background: Coronary artery disease, (CAD) is an important risk for morbidity and mortality. Because of controversial reports about relation between high-sensitivity C-reactive protein (hs-CRP) level and the severity of coronary artery stenosis, this study was done in Taleghani Hospital. Methods: In this case-control study 85 patients with CAD undergoing coronary angiography were studied. Angiography findings were based on severity of disease according to the Gensini score: <10 was classified as mild, 10 to 50 as moderate and >50 as severe. Blood samples (1mL) were collected from each patient. After centrifugation in laboratory the level of hs-CRP were measured, and classified in three levels: <1mg/L, 1 to 3 and >3mg/L respectively as mild, moderate and significant elevation of hs-CRP. Correlation of these levels with the severity of CAD was analyzed with chi-square test. Result: Out of 85 subjects, 64.7% were males mean age 55.7±7.06 years. In 28.2% the hs-CRP level were <1 mg/L, in 27.1% between 1 and 3 mg/L and in 44.7% >3mg/L. Findings revealed significant elevation of hs-CRP level in patients with moderate and severe coronary artery stenosis (p<0.01). Conclusion: Findings of this study demonstrated correlation between serum hs-CRP level and severity of coronary artery stenosis. Keywords: Gensini score, Severity of coronary stenosis, hs-CRP
Full-Text [PDF 158 kb]   (2665 Downloads)    
Type of Study: Original | Subject: Cardiology
Received: 2013/02/2 | Published: 2012/11/15

Send email to the article author

Creative Commons License
This Journal is licensed under a Creative Commons Attribution 4.0 International License  | Research in Medicine

Designed & Developed by : Yektaweb