Volume 24, Issue 1 (Spring 2000)                   Research in Medicine 2000, 24(1): 7-14 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Samak H, Haiphathali A, Mesbah Namin A. Surveying The Variations of Lipid and Lipoprotein-Cholesterol in Acute Lymphoblastic Leukemia. Research in Medicine. 2000; 24 (1) :7-14
URL: http://pejouhesh.sbmu.ac.ir/article-1-2192-en.html
Department of Hematology and Blood Bank, Tarbiat Modarres University, Tehran, Iran.
Abstract:   (1415 Views)
The importance of variations in lipid and lipoprotein-cholesterol level has been determined in many disorders including cardiovascular and metabolic ones. The following study has been achieved with the aim of determining the level of these factors and their standard variation criteria in patients with acute lymphoblastic leukemia (ALL). To meet this demand, serum lipid and lipoprotein-cholesterol were assessed in 42 patients with ALL, divided in two groups of children (under 15 years) and adults (over 15 years), in a two phase study: 1- before therapy, 2- after the first course of chemotherapy. Precipitation method and applying the acetate cellulose electrophoresis were our methods of choice. Results have shown a significant increase in TG and VLDL-C level in patients (before therapy) in comparison with the control group (112.7 to 142.2 mg/dl and 22.5 to 28.5 mg/dl, respectively), in the meantime, a significant decrease has been noted in HDL-C level (32.3 to 21.5 mg/dl). In patients with complete remission, the results have revealed significantly decrease in TG and VLDL-C levels after inducing chemotherapy (142.9 to 121mg/dl and 28.6 to 24.2 mg/dl), whereas significantly increase was determined in HDL-C level (22.0 to 29.8).
Full-Text [PDF 4825 kb]   (376 Downloads)    
Type of Study: Applicable | Subject: Radiology
Received: 2020/02/16 | Accepted: 2020/02/16 | Published: 2020/02/16

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Creative Commons License
This Journal is licensed under a Creative Commons Attribution 4.0 International License  | Research in Medicine

Designed & Developed by : Yektaweb