Volume 16, Issue 3 And 4 (January 1992)
Research in Medicine 1992, 16(3 And 4): 33-41 |
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Azizi F. Long -Term Outcome Therapy of Toxic Diffuse Goiter in Tehran. Research in Medicine 1992; 16 (3 and 4) :33-41
URL: http://pejouhesh.sbmu.ac.ir/article-1-2460-en.html
URL: http://pejouhesh.sbmu.ac.ir/article-1-2460-en.html
Shahdeed Beheshti University of Medical Sciences,Iran.
Abstract: (2200 Views)
SUMMARY
In order to evaluate the long-ter m effects of antithyroids and ahlative therapy on patients with toxic diffuse goiter (TDG) in an iodine deficient region, 206 patients were studied in Tehran. Hyperthyroidism recurred in 50%, of 80 patients treated with Methimazole (MMI), from one week to 48 months after cessation of therapy. Another 40 patients remained in remission. Of 102 patients treated with radioactive iodine (RAI), 45% became hypothyroid, 49 %,. were euthyroid and 6 %, had relapse. The rate or hypothyroidism was 58% and that of relapse was 17% in 24 Patients who under.vent suhtotal thyroidectomy. BY the end of 4 years of follow-up, 50%, treated with ant it hyroids, 51% given RAJ and 25% of patients who had surgery have remained euthyroid.
This study demonstrates good rate of remission after antithyroid therapy and high rate of hypothyroidism following thyroidectomy for patients with TDG in an area of iodine deficienc.
In order to evaluate the long-ter m effects of antithyroids and ahlative therapy on patients with toxic diffuse goiter (TDG) in an iodine deficient region, 206 patients were studied in Tehran. Hyperthyroidism recurred in 50%, of 80 patients treated with Methimazole (MMI), from one week to 48 months after cessation of therapy. Another 40 patients remained in remission. Of 102 patients treated with radioactive iodine (RAI), 45% became hypothyroid, 49 %,. were euthyroid and 6 %, had relapse. The rate or hypothyroidism was 58% and that of relapse was 17% in 24 Patients who under.vent suhtotal thyroidectomy. BY the end of 4 years of follow-up, 50%, treated with ant it hyroids, 51% given RAJ and 25% of patients who had surgery have remained euthyroid.
This study demonstrates good rate of remission after antithyroid therapy and high rate of hypothyroidism following thyroidectomy for patients with TDG in an area of iodine deficienc.
Type of Study: Original |
Subject:
Interdisciplinary (Educational Management, Educational research, Statistics, Medical education
Received: 2020/03/6 | Accepted: 2020/03/6 | Published: 2020/03/6
Received: 2020/03/6 | Accepted: 2020/03/6 | Published: 2020/03/6
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