Volume 12, Issue 1 And 2 (September 1988)                   Research in Medicine 1988, 12(1 And 2): 43-47 | Back to browse issues page

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Shahidi Dadras M, Tousi P. Angioimmunoblastic Lymphadenopathand Report of Two Rare Cases. Research in Medicine 1988; 12 (1 and 2) :43-47
URL: http://pejouhesh.sbmu.ac.ir/article-1-2488-en.html
Angioimmunoblastic Lymphadenopathand Report of Two Rare Cases
Mohammad Shahidi Dadras , Parviz Tousi
Department of Dermatolog, Loghman Hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:   (2274 Views)
Angioimmunoblastic Lymphadenopathy (AIL) is an uncommon disorder which begins  with constitutional symptoms. The majority of the patients .has generalized l?7111ph­ adenopathy, , hepatosplenomegaly and about 40% show cutaneous manifestations such as maculopapular eruption, purpura, urticaria or erythroderma. Histhopatho­Iogy of lymphnodes has a characteristic picture. The etiology of AIL is unknown but histopathologic and laboratory findings are compatible with an immunologic disorder. Most authors suggest that AIL might be a malignant disease despite its original description as a benign proliferative process, it is probably most app­ropriate to consider AIL a prelymphomatous state of immunoblastic sarcoma. Here, we report two patients with this rare disease which were seen in dermatology ward, Loghman hospital Tehran. In one of our cases AIL was associated with pyo - derma gangrenosum which has not been reported before, another case was a child which is a rare occurance who showed many unexplained skin manifestations such as sclerodermatous changes of the extremities, bilateral lymphedema, nail changes and fissured tongue. 
Keywords: Angioimmunoblastic Lymphadenopathand
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Type of Study: Case report | Subject: Interdisciplinary (Educational Management, Educational research, Statistics, Medical education
Received: 1987/04/27 | Accepted: 1987/11/2 | Published: 1988/04/21
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