Lesion of toxemia in first trimester pregnancies: Lesion of toxemia of pregnancy, comprising desidual arteriolar thickening, narrowing, degeneration, and endothelial vacuolization with trophoblastic degeneration and fibrin thrombi attached to degenerated chorionic villi, were evident in 46 (14.1 per cent) of 326 induced first trimester abortioruJ. No clinical features of toxemia were present, and fetal development was not apparently affected.