Research in Medicine

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Marandian M H, Saboori Deylami M, Zareiyan K, Azma G, Behfrooz B. Rickets Due To Prolonged Use of Antiepileptic Drugs. Research in Medicine 1977; 5 (2) :95-104
URL: http://pejouhesh.sbmu.ac.ir/article-1-2720-en.html

La therapeutique ant epileptique de longue duree provoque une profonde modification du metabolisme de la vitamine B et notamment une acceleration du catabolisme de celle-ci. 
Les auteurs rapportent un cas de ce type particulier d'osteomalacie et la revue de la lit­terature leur permet de souligner trois points essentiels: 
1 ) les besoins journaliers de la vitamine B sontaccrus chez les enfants soumis aux drogues anti-convulsives, 

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6- LIFSHITZ. F, and MacLaron, N.K: Vitamin ( D) dependent rickets in institutionalized, mentally retarded children receiving long - term anticonvulsant therapy. Journal of - pediatrics. 83, 612-620, 1973.

7- SILVER. J. Davies. T.J. Kupersmitt, E. Orme. M Petrie, A: Vajda, F. Prevalence and treatment of vitamin - D-deficiency in children on anticonvulsant drugs. Archives of Disease in childhood.

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