Volume 12, Issue 3 And 4 (February 1988)                   Research in Medicine 1988, 12(3 And 4): 0-0 | Back to browse issues page

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Roodpeyma S, Ghotbi F, Shahmohammadi A. Idiopathic Hypereosinophilic Syndrome. Research in Medicine 1988; 12 (3 and 4)
URL: http://pejouhesh.sbmu.ac.ir/article-1-2736-en.html
Idiopathic Hypereosinophilic Syndrome
Shahla Roodpeyma , Fatemeh Ghotbi , Ali-Akbar Shahmohammadi
Department of Pediatrics, Taleghani Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:   (1725 Views)
Idiopathic hypereosinophilic syndrome is a multisystem disease with peripheral blood eosinophilia of at least 6 months duration, multiple organ system involvement, and no evidence for other known causes of eosinophilia. It is characteristically a disease of middle-aged men, often has a poor prognosis and is seldom found during childhood. Heart dicsease, characterized by endomyocardial fibrosis is one of the major causes of morbidity and mortality in the idiopathic hypereosinophilic syndrome. Endomyocardial biopsy findings showed that the endothelial cells in the endocardium and of the microvasculature were the primary targets of the tissue damage. Chemotherapy of lower the eosinophil counts has resulted in marked inprovement of HES prognosis, as have agressive medical and surgical approaches to cardio­vascular complications. We report an 8 year old boy who we believe had HES with cardiovascular disfunction as mitral and tricuspid regurgitation. 
Keywords: Idiopathic Hypereosinophilic
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Type of Study: Original | Subject: Interdisciplinary (Educational Management, Educational research, Statistics, Medical education
Received: 1988/03/19 | Accepted: 1988/09/4 | Published: 1989/02/23
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