Research in Medicine

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avazpour S, nemati J, hemmatinafar M, salesi M. The effect of a combined training period (aerobic and High Intensity Interval Training) and high intensity interval training on Homocysteine and ESR in cardiovascular patients. Research in Medicine 2021; 45 (4) :40-45
URL: http://pejouhesh.sbmu.ac.ir/article-1-2937-en.html

Background and Aim: Reduction of any mobility and activity can cause many diseases as cardiovascular diseases. The aim of the present study was investigation of the effect of a combined training period (aerobic and High Intensity Interval Training) and high intensity interval training on Homocysteine and ESR in cardiovascular patients.
Materials and Methods: In the current experimental study, 32 cardiovascular patients were selected voluntarily and were randomly divided into 3 groups: combined training group (n = 10), HIIT training group (n=11), and control group (n = 11). Inclusion criteria included injection fraction greater than 30, lack of tachycardia and bradycardia, and lack of functional capacity less than 5 met, and the exclusion criteria included unwillingness to continue the activity and diagnosis by a physician. The protocol of the HIIT training group included performing 2-3 times a week of HIIT training during the first 4 weeks and performing 3 times a week of HIIT training during the second 4 weeks.
Blood samples were taken 24 hours before the first training session and 48 hours after the last training session, under the same conditions for all the three groups. Data analysis was performed using paired sample t-test, ANOVA, and post hoc with a significance level set at P˂0.05.
Results: The performing of combined exercises and HIIT was found to have a significant effect on reducing serum homocysteine levels (combined exercise (baseline values of 19.7± 1.3, after intervention 13.8 ± 2.3, P˂0/00), HIIT exercise (baseline values: 20.0± 1.3, after intervention: 16.3± 1.5, P˂0/001)) and ESR levels (combined exercise (baseline values: 27.7 ± 2.1, after intervention: 22.13 ± 1.27, P˂0/005), HIIT exercise (baseline values: 26.2 ± 2.8, after intervention: 22.9 ±2.0, P˂0/004)) compared with the control group (Homocysteine P˂0/619, ESR P˂0/306) of cardiovascular patients.
Conclusion: Combined and HIIT trainings seem to be effective in reducing homocysteine and ESR in cardiovascular patients, while the effect of combined exercise is greater than that of HIIT.