Research in Medicine

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Background: Urinary calculi comprise one of the major and widespread problems in the urinary tract. Various factors play a role in the formation of urinary stones including nutrition, weather, sex, genes, and urease producing bacteria. The incidence of urinary stones in different societies ranges from 3 to 4 percent. This survey was done in 2004 on 100 patients presenting with urinary calculi in Labaffie Nejad Hosptial . Materials and methods: Urinary calculi which had been extracted out from 100 patients, using ESWL approach, were studied. Tiny fractions of stones were put in culture tubes, (Thioglicoolate and T.S.B). Other fractions of stones were sent for chemical analysis. Result: During the analysis of 100 samples which were cultured, bacteria grew in 40 samples (40%). 53.88 percent of the stones were of mixed type. Microorganism isolated from the stones were E.coli (37.5%), S.aureus (17.5%), Candida (12%), Enterobacter (10%), Klebsiella (10%), Providencia (5%), S.epidermidis(5%), Bacillus subtilis (2.5%). There was a significant relationship between a positive culture for E.coli and Calcium oxalate stones, and also between Enterobacter and uric acid stones, (p = 0.034 in both cases). Conclusion: Bacteria, both urease producers and non–producers of urease are capable of gathering Calcium crystals and thus constitute a significant factor in the formation of urinary stones. KEYWORDS:

Keywords: Urinary calculi, bacteria, urinary infections. ESWL (extra corporal shock wave lithotripsy.

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