Volume 48, Issue 2 (8-2024)
Research in Medicine 2024, 48(2): 81-95 |
Back to browse issues page
Ethics code: 11111111111
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Ghasemi pour S, Minasian V. The Effects of Different Exercise Training on the Expression of Obesity- Related miRNAs in Iranian Society: A Review Article. Research in Medicine 2024; 48 (2) :81-95
URL: http://pejouhesh.sbmu.ac.ir/article-1-3368-en.html
URL: http://pejouhesh.sbmu.ac.ir/article-1-3368-en.html
Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran. , v.minasian@spr.ui.ac.ir
Abstract: (321 Views)
Background and Aim: Recently, there have been significant advancements in understanding the impact of microRNAs (miRNAs) on the development of diseases such as obesity. Obesity is a prevalent clinical condition linked to an elevated risk of various diseases like metabolic syndrome, type 2 diabetes, cardiovascular disease, non- alcoholic fatty liver disease, musculoskeletal disorders, and certain cancers. Studies have shown that the control of specific miRNAs, whether positive or negative, can play a role in the onset of various diseases. Conversely, there is limited knowledge about how different types of physical activity affect the expression of miRNAs, which play a crucial role in regulating metabolic processes that are essential for maintaining energy balance and preventing or treating obesity. The purpose of this study was to enhance our understanding of how various exercise protocols impact the expression of miRNAs related to obesity.
Methods: An article review method was employed to conduct a systematic review searching for studies that examined the influence of exercise on miRNAs related obesity. Various databases, including Google Scholar, Pub Med, SID, Irandoc, and Magiran, were utilized to search for articles containing keywords such as “Obesity,” “Exercise,” “Training,” and “miRNA.” Both English and Persian keywords were used in the search process. A total of 326 individuals participated in the studies reviewed, which comprised 11 articles. The effectiveness of exercise was found to vary depending on factors like the type, intensity and duration of exercise. Most studies in the country focused on the effects of aerobic exercise, particularly HIIT, on obesity-related miRNAs. In most related studies, the long- term effect of aerobic exercises has been investigated, but the effects of other methods of exercise training have been given less attention.
Conclusion: According to this research, different types of sports activities can have a beneficial impact on the levels of obesity- related miRNAs, regardless of the intensity or kind of exercise. It is believed that these markers could be useful for early detection of obesity and related non-communicable diseases. Therefore, it is suggested that in future research, the effect of various training protocols on a wide range of these miRNAs should be investigated, and more effective protocols should be introduced.
Methods: An article review method was employed to conduct a systematic review searching for studies that examined the influence of exercise on miRNAs related obesity. Various databases, including Google Scholar, Pub Med, SID, Irandoc, and Magiran, were utilized to search for articles containing keywords such as “Obesity,” “Exercise,” “Training,” and “miRNA.” Both English and Persian keywords were used in the search process. A total of 326 individuals participated in the studies reviewed, which comprised 11 articles. The effectiveness of exercise was found to vary depending on factors like the type, intensity and duration of exercise. Most studies in the country focused on the effects of aerobic exercise, particularly HIIT, on obesity-related miRNAs. In most related studies, the long- term effect of aerobic exercises has been investigated, but the effects of other methods of exercise training have been given less attention.
Conclusion: According to this research, different types of sports activities can have a beneficial impact on the levels of obesity- related miRNAs, regardless of the intensity or kind of exercise. It is believed that these markers could be useful for early detection of obesity and related non-communicable diseases. Therefore, it is suggested that in future research, the effect of various training protocols on a wide range of these miRNAs should be investigated, and more effective protocols should be introduced.
Type of Study: Review |
Subject:
Physilogy
Received: 2024/02/20 | Accepted: 2024/06/11 | Published: 2024/09/16
Received: 2024/02/20 | Accepted: 2024/06/11 | Published: 2024/09/16
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
This Journal is licensed under a Creative Commons Attribution 4.0 International License | Research in Medicine
Designed & Developed by : Yektaweb