Volume 20, Issue 2 (October 1996)
Research in Medicine 1996, 20(2): 69-73 |
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Hemmati A, Adee Beic B. A case of Shy, Drager Syndrome. Research in Medicine 1996; 20 (2) :69-73
URL: http://pejouhesh.sbmu.ac.ir/article-1-2325-en.html
URL: http://pejouhesh.sbmu.ac.ir/article-1-2325-en.html
Shaheed Beheshti University of Medical Sciences and Health Services,Iran.
Abstract: (2974 Views)
SUMMARY
Shy, Drager syndrome is multi system degeneration of the central nervous system along with pandysautonomia. It begins after age 50 and affects men twice as women. The cardinal manifestation are due to basal ganglia and orthostatic hypotension. In spite of extrapyramidal involvement the response is poor to conventional anti-Parkinsonian medications and if this is the case in a middle age person with dysautonomia one should consider the possibility of Shy, Drager as the diagnosis. So far no cause has been identified to explain the underlying disease process.
Our patient's syncopal epidsode and sever orthostatic hypotention did not respond to antiparkinson medications but fluorocortison combined with indomethacin was quite beneficial to control the above symptoms.
Shy, Drager syndrome is multi system degeneration of the central nervous system along with pandysautonomia. It begins after age 50 and affects men twice as women. The cardinal manifestation are due to basal ganglia and orthostatic hypotension. In spite of extrapyramidal involvement the response is poor to conventional anti-Parkinsonian medications and if this is the case in a middle age person with dysautonomia one should consider the possibility of Shy, Drager as the diagnosis. So far no cause has been identified to explain the underlying disease process.
Our patient's syncopal epidsode and sever orthostatic hypotention did not respond to antiparkinson medications but fluorocortison combined with indomethacin was quite beneficial to control the above symptoms.
Type of Study: Original |
Subject:
Interdisciplinary (Educational Management, Educational research, Statistics, Medical education
Received: 2020/02/23 | Accepted: 2020/02/23 | Published: 2020/02/23
Received: 2020/02/23 | Accepted: 2020/02/23 | Published: 2020/02/23
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