Volume 48, Issue 4 (2-2025)                   Research in Medicine 2025, 48(4): 0-0 | Back to browse issues page

Ethics code: IR.SSU.REC.1396.21

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Yaghmaie D, Owlia F, Akhavan-Karbassi M. Evaluation of the role of Staphylococcus aureus in Angular cheilitis. Research in Medicine 2025; 48 (4)
URL: http://pejouhesh.sbmu.ac.ir/article-1-3395-en.html
Department of oral and maxillofacial medicine, School of dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , dr.owlia@gmail.com
Abstract:   (126 Views)
Background and Aim: Angular cheilitis is a common condition among dentists. However, it does not respond well to antifungal medication, and using corticosteroids can lead to the recurrence of the lesion or resistance to the medication. This study aimed to assess the frequency of Staphylococcus aureus in patients who visited the oral and maxillofacial medicine department at Yazd dental faculty in 2017.
Methods: This case-control study was done on 163 persons. The case group contained 65 patients with Angular cheilitis and the control group consisted of 98 healthy persons. Swabs were collected and inoculated on Blood agar and Sabouraud dextrose agar cultures. Then, the cultures were carefully evaluated for the presence of Staphylococcus aureus and Candida albicans. The data were analyzed using SPSS software, Chi-square, and T-tests. The significance level was set at p < 0.05.
Results: The study was conducted on 98 healthy individuals and 65 patients. The results showed that Staphylococcus aureus was not present in either the patient group or the control group (P<0.9). A higher prevalence of angular cheilitis was observed in female patients. Additionally, there was a direct correlation between the presence of angular cheilitis and Candida albicans.
Conclusion: Based on the findings, Staphylococcus aureus was not detected in any angular cheilitis lesions. Antibiotics for treating refractory angular cheilitis should be deferred until after microbial culture.
     
Type of Study: Original | Subject: dentistry
Received: 2024/07/13 | Accepted: 2025/02/4 | Published: 2025/03/11

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