Volume 48, Issue 4 (2-2025)
Research in Medicine 2025, 48(4): 64-74 |
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Ethics code: IR.SSU.REC.1396.21
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Yaghmaie D, Owlia F, Akhavan-Karbassi M. Evaluation of the Role of Staphylococcus Aureus in Angular Cheilitis. Research in Medicine 2025; 48 (4) :64-74
URL: http://pejouhesh.sbmu.ac.ir/article-1-3395-en.html
URL: http://pejouhesh.sbmu.ac.ir/article-1-3395-en.html
Department of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , dr.owlia@gmail.com
Abstract: (396 Views)
Background and Aim: Angular cheilitis is a common condition among dental patients. However, it often responds poorly to antifungal treatment, and the use of corticosteroids can lead to lesion recurrence or medication resistance. This study aimed to assess the frequency of Staphylococcus aureus in patients who visited the Oral and Maxillofacial Medicine Department at Yazd Dental Faculty in 2017.
Methods: This case- control study included 163 participants, with 65 patients diagnosed with angular cheilitis in the case group and 98 healthy individuals in the control group. Swabs were collected and inoculated on blood agar and Sabouraud dextrose agar. The cultures were then examined for the presence of Staphylococcus aureus and Candida albicans. Data were analyzed using SPSS software, employing Chi- square and t-tests, with a significance level set at p < 0.05.
Results: The study included 98 healthy individuals and 65 patients with angular cheilitis. The results indicated that Staphylococcus aureus was not detected in either the patient or control group (p < 0.9). A higher prevalence of angular cheilitis was observed among female patients. Additionally, there was a direct correlation between the presence of angular cheilitis and Candida albicans.
Conclusion: The findings suggest that Staphylococcus aureus is not a contributing factor in angular cheilitis lesions. Therefore, antibiotic treatment for refractory cases should be postponed until microbial cultures confirm bacterial involvement.
Methods: This case- control study included 163 participants, with 65 patients diagnosed with angular cheilitis in the case group and 98 healthy individuals in the control group. Swabs were collected and inoculated on blood agar and Sabouraud dextrose agar. The cultures were then examined for the presence of Staphylococcus aureus and Candida albicans. Data were analyzed using SPSS software, employing Chi- square and t-tests, with a significance level set at p < 0.05.
Results: The study included 98 healthy individuals and 65 patients with angular cheilitis. The results indicated that Staphylococcus aureus was not detected in either the patient or control group (p < 0.9). A higher prevalence of angular cheilitis was observed among female patients. Additionally, there was a direct correlation between the presence of angular cheilitis and Candida albicans.
Conclusion: The findings suggest that Staphylococcus aureus is not a contributing factor in angular cheilitis lesions. Therefore, antibiotic treatment for refractory cases should be postponed until microbial cultures confirm bacterial involvement.
Type of Study: Original |
Subject:
dentistry
Received: 2024/07/13 | Accepted: 2025/02/4 | Published: 2025/03/11
Received: 2024/07/13 | Accepted: 2025/02/4 | Published: 2025/03/11
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