Volume 39, Issue 2 (8-2015)                   Research in Medicine 2015, 39(2): 74-80 | Back to browse issues page

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Bigdeli M, Rahnama M, Forghani M. Early postnatal radio-frequencies 900 MHz (mobile phone) exposure effects on learning, glutathione peroxidase, and glutathione reductase enzyme activity in rat brain tissue. Research in Medicine 2015; 39 (2) :74-80
URL: http://pejouhesh.sbmu.ac.ir/article-1-1329-en.html
Early postnatal radio-frequencies 900 MHz (mobile phone) exposure effects on learning, glutathione peroxidase, and glutathione reductase enzyme activity in rat brain tissue
Mohammadreza Bigdeli , Mehdi Rahnama , Mohsen Forghani
, bigdelimohammadreza@yahoo.com
Abstract:   (7323 Views)
Background: Electromagnetic fields were made by electromagnetic radiations (EMR) of mobile phone (radio-frequencies 900 MHz). Various researches have shown that there are relationships between mobile phone electromagnetic exposure and cancer and neurologic damages. The aim of our study was to investigate the effects of mobile phone electromagnetic radiations (radio-frequencies 900 MHz) on learning, brain glutathione reductase, and glutathione peroxidase activities.

Methods: The Wistar rat pups (P1) were maintained in standard conditions. In experimental group, the rat pups were exposed to EMR (radio-frequencies 900 MHz) for 3 h per day from two days old (P2) to fourteen days old (P14). After separation of male and female rats on P22, the rats were housed in the standard animal room conditions until they grew to P58. From P59 to P61, the male rats were trained three times per day for 3 days in the water maze. On P62, the behavioural assessments were measured. Then, the rats were sacrificed by means of decapitation for brain glutathione reductase and glutathione peroxidase activities assessment.

Results: The time taken to find hidden platform (35±3.8 s for control group versus 47.1±3 s for exposed to radiation group) and the time spent exhibiting freezing behaviour (2.5±0.48 s for control group versus 9.1±1.85 s for exposed to radiation

Keywords: mobile phone radiations, brain, rat, glutathione reductase, glutathione peroxidise, learning and memory.
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Type of Study: Original | Subject: Physilogy
Received: 2014/10/27 | Accepted: 2015/11/28 | Published: 2016/03/6
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